Recombinant Human Albumin - Stem Cell Therapy
Dr. Phil Morton & Dr. Daniel Shelly
This article is taken from European Biopharmaceutical Review October 2019, pages 72-75. © Samedan Ltd
To access the full October issue of the European Biopharmaceutical Review 2019, simply click here.
"From operating as a nutrient carrier, to safeguarding optimal growth conditions, commanding stabilisation of cell membranes and co-formulated proteins, working as a scavenger of free radicals, and acting as a viscosity moderator, rHA proffers a safe solution for optimised cell performance. Albumin readily coats surfaces so any unwanted interaction between cell and surface is eliminated. It can also protect cells from shear stress during processing and stabilise cells during freeze and thaw. Importantly, it does not contain any blood-derived impurities that otherwise could activate unwanted cell pathways. Additionally, recombinant albumin can help maintain the safety and efficacy of products during storage. Overall, rHA products are specifically developed to enhance the functional properties of albumin in cell culture, cryopreservation, and stem cell formulation, bestowing developers more confidence in their cell therapy."