Bio-reduction of Redox-Sensitive Albumin Conjugates in FcRn-Expressing Cells†
Lorine Brülisauer, Gina Valentino, Sakura Morinaga, Kübra Cam, Dr. Jens Thostrup Bukrinski, Prof. Dr. Marc A. Gauthier, Prof. Dr. Jean-Christophe Leroux. Agewandte Chemie Volume 53, Issue 32, August 4, 2014 , Pages 8392–8396
First published: 24 June 2014Full publication history; DOI: 10.1002/anie.201404238 l
Publication type: Veltis
"A detailed bio‐reduction analysis of redox‐sensitive albumin conjugates in two FcRn‐expressing cell lines has been performed. The obtained results indicate that the FcRn‐mediated recycling pathway is not (or is only poorly) bio‐reducing."