Albumedix Bookshelf Tunable Half-Life Technology

Tunable Half-Life Technology

Tunable Half-Life Technology

Mark Perkins

BioProcess International Friday, March 1, 2013 9:00 am

Pub type: Veltis

 

"Addressing the half-life challenge has been a focus of industry product development in recent years. Real progress has been seen in development of technologies to modulate the serum half-lives of protein-based therapeutics to meet desired specifications. Increasing hydrophobic volume (through PEGylation, fusing proteins to polyethylene glycol molecules) and FcRn-mediated recycling (albumin fusion) are common strategies. Although both have been successful in extending serum half-life, researchers continue to work on specifically designing protein half-life to achieve desired pharmacokinetics."

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Albumedix is a science-driven, biotechnology company focused on enabling the creation of superior biopharmaceuticals utilizing our albumin-based drug enhancing technologies. We partner with excellence to improve therapies for people with serious diseases. We are proud to be recognized as the world leader in recombinant human albumin with products and technologies used in clinical and marketed drugs by pharmaceutical companies worldwide. Headquartered in Nottingham, England with more than 80 people all committed to improving patient quality of life. We are just as passionate about albumin and albumin-enabled therapies today as we were when we started 30 years ago.

 

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