Albumin: From Peptides, to Proteins, to Viral Vectors03 Feb 2020
Albumedix has attended PepTalk for many years, and as the world of biopharmaceuticals expands towards more complex entities, albumin continues to play a role in the stabilisation of the most challenging APIs.
As an example of albumin’s potential in stabilising difficult biopharmaceuticals, we have presented the results obtained for glucagon, a notoriously insoluble and unstable peptide. Albumin was not only able to allow the solubilisation of this APIs in a close-to-physiological conditions, where the peptide is insoluble, but also protected it from chemical and physical degradation in accelerated stability tests.
A new stream, focusing on Cell and Gene Therapies, was present this year in PepTalk with many interesting presentations highlighting a this fast-growing area which still needs to address many technical hurdles. Overcoming these challenges will lead to the full and safe exploitation of these new technologies. In Albumedix we believe that albumin, with its multiple functionalities, will play a major role in enabling these new modalities to safely reach the market.